PRP for Hair Regrowth: An Effective Treatment for Hair Loss

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By Jason Sorgi, PA-C, MPAS

Wondering if PRP treatments for hair regrowth works? This article explains how this treatment stimulates hair growth using your own blood and what you can expect from this procedure.

Key Takeaways

• PRP therapy utilizes the patient’s own blood to rejuvenate hair follicles, making it a natural option for hair loss.

• The therapy leverages growth factors found in platelet-rich plasma to stimulate hair follicle activity, improve hair density, and reduce hair shedding.

• Combining PRP with treatments like microneedling or ACell enhances effectiveness, while ongoing maintenance sessions are crucial for long-term results.

Understanding PRP Therapy for Hair Regrowth

Platelet-Rich Plasma (PRP) therapy is a regenerative treatment that utilizes the body’s own healing capabilities to revitalize hair follicles. This quick and easy procedure involves using your own blood to promote hair regrowth, making it a natural and safe option for those experiencing hair loss. 

PRP contains a variety of growth factors and cytokines that aid in healing and stimulate new growth. Injecting PRP into the scalp aids in reversing hair loss and rejuvenating hair follicles.

Understanding what platelet-rich plasma is and how the therapy works can clarify PRP therapy.

What is Platelet-Rich Plasma?

Platelet-rich plasma (PRP) contains a high concentration of platelets than whole blood. It is a specific portion of plasma that is enriched with these cells. Prepared using concentrated platelets derived from the patient’s own blood, PRP is rich in growth factors that play a crucial role in tissue regeneration and platelet concentration. Platelet rich plasma injections are increasingly used for various therapeutic applications, including joint injections, skin rejuvenation and hair loss. 

Key growth factors in PRP, such as Fibroblast Growth Factor (FGF), Vascular Endothelial Growth Factor (VEGF), and Epidermal Growth Factor (EGF), enhance hair regrowth by stimulating stem cells in hair follicles and promoting cellular activity.

How PRP Therapy Works

PRP therapy involves drawing a small amount of blood, centrifuging it to isolate the platelets, and then injecting the concentrated PRP solution into the scalp where hair growth is needed.

Microscopic examinations have shown increases in follicular cells and vascularization in scalp tissues after PRP treatment, indicating its effectiveness in promoting hair regrowth.

The Science Behind PRP and Hair Growth

PRP therapy is designed to stimulate hair follicles and new capillaries to promote the growth of new hair. While the exact mechanism of action is not fully understood, the combination of growth factors and cytokines in PRP plays a pivotal role in revitalizing dormant hair follicles and encouraging hair regrowth. Research has shown that hair grafts preserved in PRP exhibit enhanced hair density, graft uptake, and thickness compared to those preserved in normal saline.

Additionally, combining PRP with ACell can significantly reduce hair thinning and support new hair growth by stimulating cellular regeneration. The effectiveness of PRP therapy is supported by clinical evidence, making it a reliable option for those seeking to combat hair loss.

Examining the role of growth factors in PRP and the clinical evidence supporting its use for hair growth provides further insight.

Role of Growth Factors

Platelets in the blood serve as the primary source of growth factors necessary for hair regrowth. A concentrated composition of platelets, stem cells, and growth factors in PRP significantly contributes to increased hair thickness and longer growing phase. Growth factors such as:

• Platelet-derived growth factor (PDGF)

• Insulin-like growth factor-1 (IGF-1) stimulate hair follicle activity and promote angiogenesis, leading to improved hair density. These growth factors also:

• Enhance blood flow

• Stimulate cellular turnover

These beneficial effects contribute to the reversal of hair follicle miniaturization and encourage hair regrowth.

PRP therapy has anti-apoptotic effects that help increase hair follicle cell survival, further promoting hair growth. The effectiveness of PRP in promoting hair regrowth can be influenced by factors such as the number of platelets and their concentration, with an optimal PRP composition typically involving a concentration of platelets that is two to sometimes over sixteen times higher than normal baseline levels.

Clinical Evidence

Clinical studies have shown that PRP can significantly improve hair density and reduce hair shedding in treated patients. A recent meta-analysis confirmed the efficacy of PRP treatment specifically in increasing hair density for female pattern hair loss. PRP has also shown significant hair regrowth compared to traditional treatments such as triamcinolone acetonide for conditions like alopecia areata. For most patients, PRP treatment leads to noticeable hair regrowth and improvement in hair quality.

PRP therapy may decrease shedding or lead to thicker-looking hair, enhancing the overall aesthetic appeal. Studies consistently show that PRP treatments can be used effectively for the treatment of various forms of hair loss without major side effects.

Procedure Overview: What to Expect During PRP Treatment

A typical PRP hair treatment:

• Takes between 30 to 60 minutes, making it a convenient option for those with busy schedules.

• It is advisable to consider as soon as premature hair loss is noticed to achieve the best results.

• It is best suited for individuals with thinning hair, recent hair loss, and in overall good health without chronic conditions. 

PRP therapy is a crucial option for patients experiencing hair loss, offering a non-surgical solution that leverages the body’s natural healing abilities. This hair loss treatment utilizes the benefits of PRP therapy to promote hair regrowth.

The procedure involves a few key steps, including blood draw and centrifugation, obtaining appropriate plasma layer,  followed by the injection of PRP into the scalp. Let’s break down these steps to give you a clearer picture of what to expect.

Injection Process

The next step involves injecting the concentrated PRP into the scalp in areas needing hair growth. This precise application can involve several  bolus or numerous micro injections to ensure comprehensive coverage. To ensure patient comfort, an anesthetic ring block may be administered or nitrous oxide gas used to minimize pain during the procedure.

The goal of these injections is to promote hair growth by activating weak or dormant hair follicles that have been injected.

Who Can Benefit from PRP for Hair Loss?

PRP therapy can be used to treat various types of hair loss, including androgenetic alopecia, female pattern hair loss, and alopecia areata. Individuals experiencing recent hair loss, especially those with thinning hair, are more likely to benefit from PRP therapy. Men and women with androgenic alopecia and early-onset hair loss are considered good candidates for PRP hair restoration. However, patients with active skin conditions or complete baldness should avoid PRP therapy.

Specific conditions that benefit from PRP therapy include androgenetic alopecia, female pattern hair loss, and alopecia areata.

Androgenetic Alopecia/Female Pattern Hair Loss

Androgenetic alopecia affects both genders, leading to different patterns of hair loss in men and women. PRP therapy can help individuals with androgenetic alopecia by stimulating hair follicles and promoting hair regrowth. Targeting the underlying cause of hair thinning, PRP therapy helps maintain hair growth and improve density and thickness.

Alopecia Areata

Alopecia areata is an autoimmune disorder causing non-scarring hair loss, affecting around 2% of the population at some point in their lives. PRP treatment may offer quicker and more effective results than traditional treatments like corticosteroid injections for alopecia areata in the field of cosmetic dermatology.

Promoting hair follicle regeneration, PRP therapy can help regrow hair and restore confidence for those affected by alopecia areata.

Combining PRP with Other Treatments

Combining PRP therapy with other treatments can enhance the effectiveness of hair regrowth efforts. PRP injections are often done in combination with microneedling to enhance the stimulation naturally of hair growth factors. Additionally, PRP therapy can be paired with medications to encourage further growth. The PRP therapy was a crucial component in the transformation of a Norwood 6-7 patient, providing a foundation for successful surgical procedures.

Two popular combinations include PRP with ACell and PRP with microneedling.

PRP and ACell

Boston Hair Restoration® combines standard PRP therapy with an extracellular matrix product called ACell to enhance results. ACell is a porcine-derived protein matrix developed to accelerate wound healing that helps growth factors remain active in the scalp for extended periods.

The combination of PRP and ACell has shown enhanced regenerative effects and improved longevity of results compared to traditional PRP treatments alone.

PRP with Microneedling

Combining PRP with microneedling enhances the treatment’s effects on hair regrowth. Microneedling creates micro-injuries that promote better absorption of PRP, allowing growth factors to penetrate deeper into the scalp.

This combination can significantly increase hair regrowth by enhancing the absorption and effectiveness of PRP.

Expected Results and Maintenance

Patients typically need between three to six months to notice significant improvements in hair growth after PRP treatment. The treatment schedule involves:

• An initial phase of three monthly PRP treatments

• Boosters every six months

• Ongoing treatments to maintain the benefits of PRP therapy, with maintenance sessions generally scheduled every 4-6 months after achieving desired results.

Knowing the expected results timeline and the importance of maintenance treatments aids in managing expectations and ensuring long-term success.

Initial Results Timeline

Reduced shedding can be expected around two to three months after the first PRP session. Patients typically require four sessions of PRP combined with microneedling to achieve substantial improvement in hair growth.

Most patients begin noticing decreased shedding within 6-8 weeks, with visible thickening and new growth appearing after 3-4 months.

Long-Term Maintenance

Ongoing maintenance sessions are recommended every six to twelve months to retain hair growth results. These maintenance treatments are essential to maintain hair growth and ensure the continued effectiveness of PRP therapy.

Safety and Side Effects

PRP therapy is considered safe as it uses the patient’s own blood products, eliminating the risk of communicable diseases. The therapy is generally well-tolerated and has a low risk of serious complications. However, reactions to injection therapies can vary, and patients should be aware of the potential side effects.

The lack of standardized treatment protocols poses challenges in PRP application, making provider experience critical. Awareness of minimal adverse effects and contraindications helps patients make informed decisions about PRP therapy.

Minimal Adverse Effects

Common side effects of PRP therapy for hair restoration include redness, tenderness, and swelling at injection sites. Patients may experience mild headaches post-treatment, but these typically resolve quickly.

The blood removal process is generally not painful, which adds to the overall comfort of the treatment.

Contraindications

Individuals taking blood thinners or having chronic diseases should consult a healthcare provider before undergoing PRP therapy. Checking that patients are not on medications or have conditions that could interfere with the treatment’s effectiveness is crucial for a safe and successful outcome.

Cost Considerations

The cost of PRP therapy is impacted by the equipment used, any additives included in the treatment, and the skill and experience of the provider. PRP therapy for hair loss involves various costs that can vary significantly based on these factors.

Knowing the cost and insurance coverage helps patients plan for the financial aspect of PRP therapy.

Treatment Costs

The typical cost for one session of PRP therapy ranges from $1,500- $3,500 in Massachusetts. Discounts may be available for patients who commit to a series of PRP treatments, making it more affordable in the long run.

However, the overall expense for multiple PRP three sessions can accumulate quickly, leading to considerable total costs.

Insurance Coverage

Many insurance plans do not cover the expenses related to PRP therapy for hair loss. Most insurance providers view PRP therapy as cosmetic, which generally excludes it from coverage. Patients often explore alternative payment options due to the lack of insurance coverage for PRP treatments.

Proving medical necessity for PRP therapy requires substantial documentation and often a healthcare provider’s support.

Choosing the Right Provider

Choosing a qualified provider is critical for the success and satisfaction of PRP therapy. Consider the following:

• Inquire about the practitioner’s qualifications and their specific experience with PRP in treating conditions similar to yours.

• Ensure the provider has mastery of various hair loss approaches to offer a comprehensive treatment plan.

• Patients typically receive a detailed explanation of the procedure.

• Patients must sign an informed consent form before treatment.

Choosing the right provider can significantly affect treatment outcomes and overall experience.

Importance of Experience

Choosing an experienced practitioner is crucial for successful PRP therapy for hair loss. The practitioner has over a decade of experience with PRP treatments, enhancing their capability in providing effective care. No standardization exists in PRP treatment protocols, making the experience of the practitioner even more vital.

Patients should find a provider they feel comfortable with to foster a supportive environment for the patient’s treatment.

Consultation Tips

When consulting with providers, ask about:

• How PRP is prepared, how layers are separated, double vs single spin

• If they use ACell

• Their experience specifically in PRP therapy for hair regrowth

Choosing an experienced practitioner is vital, as their knowledge and proficiency in administering PRP enhance the treatment’s effectiveness.

A good step is to visit the office and meet with the provider to determine the best treatment approach.

Summary

PRP therapy for hair regrowth offers a promising solution for those struggling with hair loss. By utilizing the body’s natural healing abilities, PRP therapy can stimulate hair follicles and promote new hair growth. The process involves a series of steps, from blood draw and centrifugation to precise PRP injections into the scalp. Clinical evidence supports the effectiveness of PRP therapy, and combining it with other treatments can enhance results. While the cost and lack of insurance coverage may be a consideration, choosing an experienced provider can significantly impact the success of the treatment. If you’re ready to take the next step in your hair restoration journey, PRP therapy might be the key to regaining your confidence and achieving luscious locks.

Frequently Asked Questions

How long does it take to see results from PRP therapy for hair loss?

You can expect initial results, like reduced shedding, within two to three months after the first PRP session, with visible thickening and new hair growth typically emerging after three to four months.

Are there any side effects of PRP therapy for hair restoration?

PRP therapy for hair restoration may lead to mild side effects such as redness, tenderness, and swelling at the injection sites. 

How much does PRP therapy cost?

PRP therapy typically costs between $1,500-$3500 per session, with potential discounts for those undergoing multiple treatments.

Is PRP therapy covered by insurance?

PRP therapy is typically not covered by insurance because it is considered a cosmetic procedure. Therefore, you should be prepared for out-of-pocket expenses if you choose this treatment.

Who is a good candidate for PRP therapy?

A good candidate for PRP therapy is someone experiencing recent hair loss or thinning hair. However, individuals with active skin conditions, chronic diseases, or complete baldness should may want to avoid this treatment.